Yes, Security Monitor Pro supports custom camera preview layouts.
You can right click on each preview and select 'detach'. You can then move each of the preview screens to any position on your monitor and resize it. In effect, you can create any layout you like. When you exit and restart Security Monitor Pro, it will remember the previous positions of your preview windows.
Would you be willing to give us the necessary information to test the Mobotix i25 camera? After testing we will add support for your camera to Security Monitor Pro. Please fill out the information on this page:
https://www.deskshare.com/camera-request.aspx